Case Study
Research Briefs
- Can restrictive diets for improving gut health lead to psychological harm?
- Can a cognitive behavioral therapy app improve GI symptoms and reduce fear of food?
Practitioner Question
Case Study
Clinical Review
Practitioner Question
Case Study
Research Briefs
- Does pelvic floor biofeedback therapy improve bloating?
- Does rotating antimicrobials lead to better outcomes in SIBO patients?
- Does a simple exercise intervention improve bloating?
Case Study
Research Briefs
- Is the low FODMAP diet more effective than medication for improving IBS?
- Are probiotics better than medications for IBS?
Practitioner Question
Case Study:
Research Briefs:
- Does exercise or sauna lead to better detoxification of heavy metals?
- Does N-acetylcysteine reduce airway reactivity to air pollution?
Practitioner Tip:
Case Study:
Research Briefs:
- Best Dietary Treatments for Eosinophilic Esophagitis
- Is exercise helpful for improving post-COVID fatigue?
Practitioner Tip:
Case Study:
Research:
- Are Probiotics Useful for Improving Body Composition?
- Exercise Interventions and Body Composition
- Dietary Interventions and Body Composition
Listener Question:
Case Study:
Research:
Practitioner Question:
Case Study:
Clinical Review:
Practitioner Question:
Case Studies:
- Simple gut care addresses significant food reactivity and colitis (Julianna)
- SIBO patient with food reactions resolved symptoms without antimicrobials (Karen)
Research:
- 4 Studies on the “Weekend Warrior”
- Physical Activity Patterns and Mortality: The Weekend Warrior and Activity Bouts
- Association of “Weekend Warrior” and Other Leisure Time Physical Activity Patterns With Risks for All-Cause, Cardiovascular Disease, and Cancer Mortality
- The “Weekend Warrior” and Risk of Mortality
- Leisure time physical activity and mortality: a detailed pooled analysis of the dose-response relationship
Case Studies:
- Microscopic Lymphocytic Colitis Resolved with Foundational Gut Support (Vickie)
- PTSD, Eating Disorders, and IBS (Jane)
Research:
Case Studies:
Research:
- Probiotics’ ability to degrade aflatoxin
- Probiotic protects against zearalenone induced damage during pregnancy
Practitioner Tip:
Clinical Review:
Case Studies:
Case Study:
Clinical Review:
Research Review:
- Use of Fecal Calprotectin in your IBD patients
- Rapid-Fire Research Reviews:
- Is Sauna Safe in Pregnancy?
- Probiotics for preventing acute upper respiratory tract infections
- Variability of fecal calprotectin in healthy patients without colonic inflammation or neoplasm
- Bile acid binding affinity of raw foods
- Bile acid binding of steam cooked foods
Case Studies:
- Iterative Care: Limbic Retraining and Supplementation for Mast Cell Activation Provide Remarkable Benefits (Ashley)
- Avoiding the Hormone Replacement, Over-Testing, and Off-Label Medication Traps (Paul)
Research:
- Is Metformin An Effective Treatment for Hashimoto’s Thyroiditis?
- Can Vitamin D and Omega 3 Fats Prevent the Development of Symptomatic Autoimmune Disease?
Practitioner Question:
Case Studies:
- Sleep disordered breathing interventions improve insomnia and fatigue (Mark)
- Questionable case of polymyalgia rheumatica resolved with basic GI-focused care (Jim)
Research:
Practice Tip:
Case Studies:
- Basic, Conservative Functional Medicine Improves Insomnia, Depression, and GI Health (Ashley)
- Severe IBD Addressed Rapidly With Diet and GI Supportive Therapies (Steve)
Research:
- Is Hormone Replacement Therapy Safe for Women with a Previous Diagnosis of Breast Cancer?
- How Do I Treat Subclinical Hypothyroidism?
Practice Tip:
Case Study:
Research:
- Herbal Treatment for Post Menopausal Symptoms
- Distribution and relevance of Dientamoeba fragilis and Blastocystis species in gastroenteritis: results from a case-control study
- AGA Clinical Practice Guidelines on the Gastrointestinal Evaluation of Iron Deficiency Anemia
- Rapid-Fire Research – Ultra-concise summaries of noteworthy studies.
- Proton Pump Inhibitors Do Not Reduce the Risk of Esophageal Adenocarcinoma in Patients with Barrett’s Esophagus: A Systematic Review and Meta-Analysis
- Highly bioavailable curcumin derivative ameliorates Crohn’s disease symptoms: A randomized, double-blind, multicenter study
- Clinical efficacy of Saccharomyces boulardii or metronidazole in symptomatic children with Blastocystis hominis infection
- Association between Sauna Bathing and Fatal Cardiovascular and All-Cause Mortality
Practitioner Question:
Practice Tip:
Case Study:
Research:
- Effect of synbiotics and probiotics supplementation on autoimmune diseases: A systematic review and meta-analysis of clinical trials
- Igg Food Antibody Guided Elimination-Rotation Diet Was More Effective than FODMAP Diet and Control Diet in the Treatment of Women with Mixed IBS—Results from an Open Label Study
- Rapid-Fire Research – Ultra-concise summaries of noteworthy studies.
- A Low-FODMAP Diet Improves the Global Symptoms and Bowel Habits of Adult IBS Patients: A Systematic Review and Meta-Analysis
- Excretion of Heavy Metals and Glyphosate in Urine and Hair Before and After Long-Term Fasting in Humans
- Diagnostic yield of endoscopy in irritable bowel syndrome: A nationwide prevalence study 1987-2016
Practice Development:
Case Study:
Research:
- Impact of the Swank and Wahls elimination dietary interventions on fatigue and quality of life in relapsing-remitting multiple sclerosis: The WAVES randomized parallel-arm clinical trial
- Prebiotics and probiotics for depression and anxiety: A systematic review and meta-analysis of controlled clinical trials
- Rapid-Fire Research – Ultra-concise summaries of noteworthy studies.
- Chronic spontaneous urticaria and internal parasites–a systematic review
- Effects of Quercetin on Blood Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
- The role of probiotic bacteria in managing periodontal disease: a systematic review
Practice Tip:
Case Study:
Research:
- Diagnosis of mast cell activation syndrome: a global “consensus-2”
- Effect of a Single High Dose of Vitamin D3 on Hospital Length of Stay in Patients With Moderate to Severe COVID-19
- Report on Absorption of magnesium sulfate (Epsom salts) across the skin
- Blood, Urine, and Sweat (BUS) Study: Monitoring and Elimination of Bioaccumulated Toxic Elements
- Rapid-Fire Research – Ultra-concise summaries of noteworthy studies.
- Dietary Flaxseed as a Strategy for Improving Human Health
- Prevention of Influenza Episodes With Colostrum Compared With Vaccination in Healthy and High-Risk Cardiovascular Subjects: The Epidemiologic Study in San Valentino
- Mixed mold mycotoxicosis: Immunological changes in humans following exposure in water-damaged buildings
Practitioner Question:
Practice Tip:
Case Study:
Research:
Practitioner Question:
Case Study:
Research:
- Clinical Review: The Role of Fungal-Based Testing in GI Conditions
- Rapid-Fire Research – Ultra-concise summaries of noteworthy studies.
- Effects of select dietary supplements on the prevention and treatment of viral respiratory tract infections: A systematic review of randomized controlled trials
- Preventing Respiratory Tract Infections by Synbiotic Interventions: A Systematic Review and Meta-Analysis of Randomized Controlled Trial
Practitioner Tip:
Case Study:
Research:
- A Review of the Mechanism of Injury and Treatment Approaches for Illness Resulting from Exposure to Water-Damaged Buildings, Mold, and Mycotoxins
- Rapid-Fire Research – Ultra-concise summaries of noteworthy studies.
- Omega-3 Fatty Acids and Atrial Fibrillation
- Insufficient Sleep Undermines Dietary Efforts to Reduce Adiposity
- Sleep duration affects risk for ulcerative colitis: A prospective cohort study
- Extended-Release Lovastatin Does not improve spontaneous bowel movements in patients with IBS-C – Phase 2b study results
Practitioner Tip:
Case Study:
Research:
- Important Updates to the Thyroid Treatment Algorithm – Clinical History, Screening, and Treatment
- Rapid-Fire Research – Ultra-concise summaries of noteworthy studies.
- Clinical Outcomes After Discontinuation of Thyroid Hormone Replacement: A Systematic Review and Meta-Analysis
- The effects of synbiotic supplementation on thyroid function and inflammation in hypothyroid patients: A randomized, double‑blind, placebo‑controlled trial
Case Study:
Research:
- Thyroid Algorithm Updates (Dr. Ruscio’s Updates & Review)
- Non-gastrointestinal symptoms of irritable bowel syndrome: An office-based clinical survey
- Rapid-Fire Research – Ultra-concise summaries of noteworthy studies
- Short-course Rifaximin therapy efficacy and lactulose hydrogen breath test in Chinese patients with diarrhea-predominant irritable bowel syndrome
- Insufficient evidence to support the clinical efficacy of selenium supplementation for patients with chronic autoimmune thyroiditis
Case Study:
- Intractable Anaphylaxis and Eczema in a 21-month-old Child (John Michael)
Research:
- The Role of Modified Citrus Pectin as an Effective Chelator of Lead in Children Hospitalized with Toxic Lead Levels
- The Effect of Modified Citrus Pectin on Urinary Excretion of Toxic Elements
- Binding Rather Than Metabolism May Explain the Interaction of Two Food-Grade Lactobacillus Strains with Zearalenone and Its Derivative a-Zearalenol
- Rapid-Fire Research – ultra-concise summaries of noteworthy studies.
- Ability of dairy strains of lactic acid bacteria to bind a common food carcinogen, aflatoxin B1
- Exogenous melatonin as a treatment for secondary sleep disorders: A systematic review and meta-analysis
- Evidence for the efficacy of melatonin in the treatment of primary adult sleep disorders
- The use of exogenous melatonin in delayed sleep phase disorder: a meta-analysis
Practitioner Question:
Case Study:
Research:
- Exploration of Recent Medscape Article (MTHFR & Folic Acid): Online Misinformation Fuels a Fight Over Folic Acid
Case Study:
- Brain-Gut Connection, An Example of When Limbic Retraining Can Yield Substantial Improvements. (Rebecca)
Research:
- GI-MAP: To Use or Not to Use? A Review of a recent study on and the evidence for the GI-MAP stool test & functional medicine stool pathogen testing in general
- Rapid-Fire Research – Ultra-concise summaries of noteworthy studies.
- Effects of a Paleolithic Diet on Cardiovascular Disease Risk Factors: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
- Exercise and gut immune function: evidence of alterations in colon immune cell homeostasis and microbiome characteristics with exercise training
Case Study
- Patient responds to gut-directed therapy and no longer needs thyroid medication after suspicious hypothyroid diagnosis, Guest Case Study by Gavin Guard, PA-C (Sally)
Research
- Clinical Review: Combination T4/T3 Therapy: Does the Ratio Matter?
- Rapid-Fire Research – ultra concise summaries of noteworthy studies
- Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder: A Randomized Clinical Trial
- Effects of a Fermented Dairy Drink Containing Lacticaseibacillus paracasei subsp. paracasei CNCM I-1518 (Lactobacillus casei CNCM I-1518) and the Standard Yogurt Cultures on the Incidence, Duration, and Severity of Common Infectious Diseases: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Practitioner Tip
Case Study
Research
- Clinical Summary: Exocrine Pancreatic Insufficiency
- Rapid-Fire Research – ultra concise summaries of noteworthy studies
- Does a glucose-based hydrogen and methane breath test detect bacterial overgrowth in the jejunum?
- Effect of Vitamin D Supplementation on Fecal Microbiota: A Randomized Clinical Trial
- The effects of high doses of vitamin D on the composition of the gut microbiome of adolescent girls
Practitioner Question
Case Study
- Improvement of mental health, metabolic health, and normalization of fecal calprotectin in 4 months. (Ashley)
Research
- Biochemical Markers in the Urine Associated with Gastrointestinal Mold-Overgrowth are Linked with Elevated Urinary Mycotoxins in Patients with Suspected Mold Illness
- A distinct gut microbiota composition in patients with ankylosing spondylitis is associated with increased levels of fecal calprotectin
- Small intestinal microbial dysbiosis underlies symptoms associated with functional gastrointestinal disorders
- Rapid-Fire Research – ultra concise summaries of noteworthy studies
- Low Dose Naltrexone: Side Effects and Efficacy in Gastrointestinal Disorders
- Association of Healthy Lifestyle with Years Lived Without Major Chronic Diseases
- Separating “good” from “bad” fecal dysbiosis – Evidence from two cross-sectional studies.
- Severe intestinal dysbiosis is prevalent in primary Sjögren’s syndrome and is associated with systemic disease activity
- Short-term diet change alters microbial diversity and triggers GI symptoms
Practitioner Tip
Case Study
- Pediatric Hypothyroidism and Gut Dysfunction: Combining Traditional and Functional Approaches. (Kyle)
Research
- Health Coaching: An Evidence-Based Review: Part I
- Rapid-Fire Research – ultra concise summaries of noteworthy studies
- Perioperative Probiotics or Synbiotics in Adults Undergoing Elective Abdominal Surgery: A Systematic Review and Meta-analysis of Randomized Controlled Trials
- Randomized Trial of Lactin-V to Prevent Recurrence of Bacterial Vaginosis
- Association of Daily Step Count and Step Intensity With Mortality Among US Adults
Practitioner Tip
Case Study:
- Hypothyroid Case Did Not Respond to Levothyroxine, Did NOT Require Combination Therapy, GI Support Resolved Symptoms. (Monica)
Research:
- 8 False Claims 60 Minutes Made About Probiotics
- Rapid-Fire Research – ultra concise summaries of noteworthy studies
- Effect of Probiotic Supplementation on Migraine Prophylaxis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
- Associations Between Migraine, Celiac Disease, Non-Celiac Gluten Sensitivity and Activity of Diamine Oxidase
- Association Between Levothyroxine Treatment and Thyroid-Related Symptoms Among Adults Aged 80 Years and Older With Subclinical Hypothyroidism | Endocrinology
Practitioner Question:
Case Study:
- Recovery from Herbal Antimicrobials After Misguided Functional Medicine Gives a Patient C. difficile, Guest Case Study by Dr. Robert Abbott (Chris)
Research:
- A Lifestyle (Dietary) Intervention Reduces Tiredness in Children with Subclinical Hypothyroidism, a Randomized Controlled Trial
- Systematic Review with Meta-Analysis: Fecal Calprotectin as a Surrogate Marker for Predicting Relapse in Adults with Ulcerative Colitis
- Efficacy of Fecal Microbiota Transplantation for Patients with Irritable Bowel Syndrome in a Randomized, Double-Blind, Placebo-Controlled Study
- Rapid-Fire Research – ultra concise summaries of noteworthy studies
- The Autoimmune Protocol Diet Modifies Intestinal RNA Expression in Inflammatory Bowel Disease
- Thyroid Disease in Pregnancy: ACOG Practice Bulletin, Number 223
- Ultra-Processed Diets Cause Excess Calorie Intake and Weight Gain: An Inpatient Randomized Controlled Trial of Ad Libitum Food Intake
Practice Tip
Case Study:
- Hydrogen Sulfide SIBO and Improvement in Interstitial Cystitis by Treating the Basics, Guest Case Study by Dr. Joe Mather (Kathy)
Research:
- Association of Frequency of Organic Food Consumption with Cancer Risk
- Efficacy of the Autoimmune Protocol Diet for Inflammatory Bowel Disease
- Eating Disorders in Adolescents with Chronic Gastrointestinal and Endocrine Diseases
- Rapid-Fire Research – ultra concise summaries of noteworthy studies
- Effect of Coenzyme Q10 Supplementation on Clinical Features of Migraine: A Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials
- Association Between Inflammatory Bowel Diseases and Celiac Disease: A Systematic Review and Meta-Analysis
- Safety and Feasibility of Various Fasting-Mimicking Diets Among People with Multiple Sclerosis
Practitioner Question of the Month
Case Study:
- Over-testing and Incorrect Hypothyroid Diagnosis Leads to Needless Patient Suffering – FFMR Model Saves the Day Again, Guest Case Study by Dr. Robert Abbott (Susan)
Research:
- Significance of Anti-TPO as an Early Predictive Marker in Thyroid Disease
- Human helminth therapy to treat inflammatory disorders – where do we stand?
- Weight-loss interventions and gut microbiota changes in overweight and obese patients: A systematic review.
- Rapid-Fire Research – ultra concise summaries of noteworthy studies
- Role of Probiotics in Prophylaxis of Helicobacter pylori Infection.
Case Study:
- Overtesting & Overuse of Supplement Protocols in Functional Medicine, Guest Case Study by Dr. Robert Abbott (Michael)
Research:
- Probiotics Protect Against Cold, Flu, and Respiratory Tract Infection
- Vitamin D therapy in inflammatory bowel diseases: who, in what form, and how much?
- Treatment of refractory and severe hypothyroidism with sublingual levothyroxine in a liquid formulation.
- Rapid-Fire Research – ultra concise summaries of noteworthy studies
- Effect of probiotic supplementation in pregnant women: a meta-analysis of randomized controlled trials.
Case Study:
- Histamine Intolerance, Medication Reduction & Lifestyle Changes Resolve a ‘Chronic & Complex’ Case, Guest Case Study by Dr. Ronit Mor (Ellen)
Research:
- Systematic review: Quality of trials on the symptomatic effects of the low FODMAP diet for irritable bowel syndrome.
- Microbiota and Thyroid Interaction in Health and Disease.
- Personalized Nutrition by Prediction of Glycemic Responses.
- Rapid-Fire Research – ultra concise summaries of noteworthy studies
- Systematic review with meta-analysis: the prevalence of small intestinal bacterial overgrowth in inflammatory bowel disease.
- The Convergence of Bacterial Overgrowth, Systemic Inflammatory Biomarkers, and Anti-Vinculin Antibodies in Determining the Response to Rifaximin Treatment in Diarrhea-Predominant IBS (D-IBS) Subjects
Case Study:
Research:
- American College of Gastroenterology: monograph on the management of irritable bowel syndrome and chronic idiopathic constipation
- Effects of regulating intestinal microbiota on anxiety symptoms: A systematic review
- Brain fogginess, gas and bloating: A link between SIBO, probiotics and metabolic acidosis
- Rapid-Fire Research – Ultra concise summaries of noteworthy studies
- The administration of probiotics and synbiotics in immune-compromised adults: is it safe?
- Effect of probiotics on depressive symptoms: A meta-analysis of human studies
Case Study
- Severe IBD with SIBO and anemia, Guest Case Study by Dr. Ilana Gurevich (Emily)
Research
- Bacillus spp. Spores – A Promising Treatment Option for Patients with Irritable Bowel Syndrome
- Investigation of iron deficiency anemia
- SYMPOSIUM REPORT: An Evidence-Based Approach to IBS and CIC: Applying New Advances to Daily Practice: A Review of an Adjunct Clinical Symposium of the American College of Gastroenterology Meeting October 16, 2016 • Las Vegas, Nevada.
- Rapid-Fire Research: Ultra-Concise Summaries of Noteworthy Studies
- Memory and Brain Amyloid and Tau Effects of a Bioavailable Form of Curcumin in Non-Demented Adults: A Double-Blind, Placebo-Controlled 18-Month Trial.
- Gluten-induced symptoms in diarrhea-predominant irritable bowel syndrome are associated with increased myosin light chain kinase activity and claudin-15 expression.
Case Study
Research
- Mood Disorders and Gluten: It’s Not All in Your Mind! A Systematic Review with Meta-Analysis
- Is SIBO A Real Condition?
- Production and Use of Hymenolepis diminuta Cysticercoids as Anti-Inflammatory Therapeutics.
- Rapid-Fire Research – Ultra-concise summaries of noteworthy studies
- Treatment of irritable bowel syndrome with probiotics. An etiopathogenic approach at last?
Practitioner Question of the Month
Case Study
Research
- Dysbiosis or Adaptation: How Stable is the Gut Microbiome?
- Current evidence for the treatment of hypothyroidism with levothyroxine/levotriiodothyronine combination therapy versus levothyroxine monotherapy
- Pesticide exposure and risk of Alzheimer’s disease a systematic review and meta-analysis
- Rapid-Fire Research – ultra concise summaries of noteworthy studies
- Breath tests for small intestinal bacterial overgrowth diagnosis: a systematic review with meta-analysis
Case Study
Research
- Ileocecal Valve & SIBO: Dr. Ruscio’s Mini-review
- Lead and cadmium exposure, higher thyroid antibodies and thyroid dysfunction in Chinese women
- Mast cells at the crossroads of microbiota and IBD
- Rapid-Fire Research – ultra concise summaries of noteworthy studies
- Perspective: Fundamental Limitations of the Randomized Controlled Trial Method in Nutritional Research: The Example of Probiotics
- Serum Thyroglobulin-A Sensitive Biomarker of Iodine Nutrition Status and Affected by Thyroid Abnormalities and Disease in Adult Populations
Case Study
Research
- Dietary carbohydrate intake and mortality: A prospective cohort study and meta-analysis.
- Efficacy of the Autoimmune Protocol Diet as Part of a Multi-Disciplinary, Supported Lifestyle Intervention for Hashimoto’s Thyroiditis.
- Iron deficiency without anemia – a clinical challenge.
Case study
Research
- Small intestinal microbial dysbiosis underlies symptoms associated with functional gastrointestinal disorders
- Neurological Dysfunction in Coeliac Disease and Non-Coeliac Gluten Sensitivity.
- Rapid-Fire Research – ultra concise summaries of noteworthy studies
- Urinary Iodine Concentration Is Inversely Associated With Thyroglobulin Antibodies.
- Selenium Supplementation In Patients With Subclinical Hypothyroidism Affected By Autoimmune Thyroiditis: Results Of The SETI Study.
- Epithelial Response To Butyrate Diminished In Active IBD
Practice Tip
Case Study
Research
- Dr. Ruscio’s Thyroid Medication Review: T4 Versus Combination Therapy (T4+T3)
- The Gut-Thyroid Connection, Profound but Underappreciated: Dr. Ruscio’s presentation at the LDN conference in June 2019.
- Rapid-Fire Research – ultra concise summaries of noteworthy studies
- Randomized placebo-controlled trial of dietary glutamine supplements for post-infectious irritable bowel syndrome
- Effect of vitamin D3 supplementation on blood pressure in adults: An updated meta-analysis
- Thyroid-stimulating hormone (TSH) serum levels and risk of spontaneous abortion: A prospective population-based cohort study.
Case Study
Research
Practice Bonus
Case Study
Research
- Effects of Prebiotics vs a Diet Low in FODMAPs in Patients With Functional Gut Disorders.
- Treatment of hypothyroidism with levothyroxine plus liothyronine: a randomized, double-blind, crossover study.
- Mediterranean Diet and Other Dietary Patterns in Primary Prevention of Heart Failure and Changes in Cardiac Function Markers: A Systematic Review.
- Rapid-Fire Research – ultra-concise summaries of noteworthy studies.
- The relationship between iron status and thyroid hormone concentration in iron-deficient adolescent Iranian girls.
- Serum Ferritin as a Marker of Thyroid Hormone Action on Peripheral Tissues.
- Association between serum ferritin and thyroid hormone profile in hypothyroidism.
Practitioner Question of the Month
Practice Tip
Case Study
Research
- Dr. Rusico’s Comparison of Two Popular DNA-based Stool Tests
- Secretome of Intestinal Bacilli: A Natural Guard against Pathologies
- Why Is Working Memory Performance Unstable? A Review of 21 Factors
- Rapid-Fire Research – Ultra-Concise Summaries of Noteworthy Studies
- Guidelines for the investigation of chronic diarrhea in adults: British Society of Gastroenterology, 3rd edition
Practitioner Question of the Month & Practice Tip
Case Study
Research
- Effect of Low-Fat vs Low-Carbohydrate Diet on 12-Month Weight Loss in Overweight Adults and the Association with Genotype Pattern or Insulin Secretion: The DIETFITS Randomized Clinical Trial
- Assessment of Anti-Vinculin and Anti-Cytolethal Distending Toxin B Antibodies in Subtypes of Irritable Bowel Syndrome
- Ferritin & Hypothyroid – Multiple nutritional factors and thyroid disease, with particular reference to autoimmune thyroid disease.
- Thyroid Algorithm Update
Practitioner Question of the Month
Practice Tip
Case Study
Research
- Vitamin D Treatment in Patients with Hashimoto’s Thyroiditis may Decrease the Development of Hypothyroidism.
- Effects of Long-Term Combination LT4 and LT3 Therapy for Improving Hypothyroidism and Overall Quality of Life.
- Non-Celiac Gluten Sensitivity: All Wheat Attack is Not Celiac
- Rapid-Fire Research – Ultra-Concise Summaries of Noteworthy Studies
- The role of low fermentable oligosaccharides, disaccharides, monosaccharides, and polyol diet in nonceliac gluten sensitivity.
- A low FODMAP diet is associated with changes in the microbiota and reduction in breath hydrogen but not colonic volume in healthy subjects.
- Recommendations for treatment of hypothyroidism with levothyroxine and levotriiodothyronine: A 2016 position statement of the Italian Society of Endocrinology and the Italian Thyroid Association.
- Effectiveness and safety of calcium and vitamin D treatment for postmenopausal osteoporosis.
Practitioner Question of the Month
Practice Tip
Case Study
Research
- Dr. Ruscio’s Review of Zonulin Testing for Leaky Gut
- Re-Challenging FODMAPs: The low FODMAP diet phase two
- Rapid-Fire Research – Ultra-concise summaries of noteworthy studies.
- Autologous stem-cell transplantation in treatment-refractory Crohn’s disease: An analysis of pooled data from the ASTIC trial
- Selective expression of histamine receptors H1R, H2R, and H4R, but not H3R, in the human intestinal tract.
- Using Hashimoto thyroiditis as the gold standard to determine the upper limit value of thyroid stimulating hormone in a Chinese cohort.
- Blocking nocturnal blue light for insomnia: A randomized controlled trial
Practitioner Question of the Month
Practice Tip
Case Study
Research
- Mechanism, Clinical Studies and Distinctive Nutritional Requirement of Oral Immunoglobulins in IBS-D and SIBO
- The Effect of Gluten-Free Diet on Thyroid Autoimmunity in Drug-Naïve Women with Hashimoto’s Thyroiditis: A Pilot Study
- Fluctuation of zonulin levels in blood vs. stability of antibodies
- Rapid-Fire Research – Ultra-concise summaries of noteworthy studies
- A low FODMAP gluten-free diet improves functional gastrointestinal disorders
- Overall Mental Health of Celiac Disease Patients: A Randomized Controlled Trial
- Evaluation of serum-derived bovine immunoglobulin protein isolate in subjects with diarrhea-predominant irritable bowel syndrome
- Association of thyroid hormone therapy with quality of life and thyroid-related symptoms in patients with subclinical hypothyroidism: A systematic review and meta-analysis
- Thyroxine and triiodothyronine content in commercially available thyroid health supplements
Practitioner Question of the Month
Practice Tip
Case Study
Research
- Re-Challenge Studies in Non-celiac Gluten Sensitivity: A Systematic Review and Meta-Analysis
- To Treat or Not To Treat H. pylori – Dr. Ruscio’s Review of H. pylori Treatment Consensus Data
- Clinical experience with the use of anti-CdtB and anti-vinculin antibodies in patients with diarrhea in Mexico
- Rapid-Fire Research – Ultra-concise summaries of noteworthy studies.
- Update on dietary therapy for eosinophilic esophagitis in children and adults
- Prucalopride succinate for the treatment of constipation: An update
- Parity and 11-Year Serum Thyrotropin and Thyroid Autoantibody Change: A Longitudinal Population-Based Study
- Effects of probiotics consumption on lowering lipids and CVD risk factors: A systematic review and meta-analysis of randomized controlled trials
- Meta-Analysis: Effects of Probiotic Supplementation on Lipid Profiles in Normal to Mildly Hypercholesterolemic Individuals
Practitioner Question of the Month
Practice Tip
Case Study
Research
- Histamine-reduced diet and increase of serum diamine oxidase correlating to diet compliance in histamine intolerance.
- Mast cell activation disease: a concise practical guide for diagnostic workup and therapeutic options.
- Small Intestinal Bacterial Overgrowth and Irritable Bowel Syndrome: Bridge between Functional Organic Dichotomy.
- Rapid-Fire Research – Ultra-concise summaries of noteworthy studies
- Serum zonulin in patients with inflammatory bowel disease: A pilot study
- Trichuris suis ova therapy in inflammatory bowel disease: A meta-analysis
- Type of fish consumed and thyroid autoimmunity in pregnancy and postpartum.
- Helicobacter pylori CagA antibodies and thyroid function in latent autoimmune diabetes in adults.
- Blocking nocturnal blue light for insomnia: A randomized controlled trial
Practitioner Question of the Month
Practice Tip
Case Study
Research
- Non-celiac gluten sensitivity: people without celiac disease avoiding gluten—is it due to histamine intolerance?
- Serum-derived bovine immunoglobulin/protein isolate therapy for patients with refractory irritable bowel syndrome
- A review of the use of biotin for hair loss
- Rapid-Fire Research – Ultra-concise summaries of noteworthy studies
- Serial Frozen Fecal Microbiota Transplantation in the Treatment of Chronic Intestinal Pseudo-Obstruction: A Preliminary Study
- Escherichia coli Nissle 1917 in Ulcerative Colitis Treatment: Systematic Review and Meta-Analysis
- Selenium Supplementation Significantly Reduces Thyroid Autoantibody Levels in Patients with Chronic Autoimmune Thyroiditis: A Systematic Review and Meta-Analysis
- Iodine Nutrition Status and Thyroid Disorders: A Cross-Sectional Study from the Xinjiang Autonomous Region of China
Practitioner Question of the Month
Practice Tip
Case Study
Research
- A concise, practical guide to diagnostic assessment for mast cell activation disease
- A Paleolithic-type diet results in iodine deficiency: A 2-year randomized trial in postmenopausal obese women
- Exercise Modifies the Gut Microbiota with Positive Health Effects
- Rapid-Fire Research – Ultra-concise summaries of noteworthy studies
- Functional 13C-urea and glucose hydrogen/methane breath tests reveal a significant association of small intestinal bacterial overgrowth in individuals with active Helicobacter pylori infection.
- Differences of microbiota in small bowel and feces between irritable bowel syndrome patients and healthy subjects.
- Unfavorable Course of Subclinical Hypothyroidism in Children with Hashimoto’s Thyroiditis Compared to Those with Isolated Non-Autoimmune Hyperthyrotropinemia.
- Tablet and oral liquid L-thyroxine formulation in the treatment of naïve hypothyroid patients with Helicobacter pylori infection.
- Retrospective Study of Patients Switched from Tablet Formulations to a Gel Cap Formulation of Levothyroxine: Results of the CONTROL Switch Study
Practitioner Question of the Month
Practice Tip
Case Study
Research
- The prevalence, incidence and natural course of positive antithyroperoxidase antibodies in a population-based study: Tehran Thyroid Study
- A concise review of Hashimoto thyroiditis (HT) and the importance of iodine, selenium, vitamin D and gluten on the autoimmunity and dietary management of HT patients. Points that need more investigation
- Effect of free triiodothyronine concentration on the quality of life of patients treated with levothyroxine
- Rapid-Fire Research – Ultra-concise summaries of noteworthy studies
- N-acetylcysteine as a powerful molecule to destroy bacterial biofilms. A systematic review
- Female hormones influence the vaginal microbiota
- Functional 13C-urea and glucose hydrogen/methane breath tests reveal a significant association of small intestinal bacterial overgrowth in individuals with active Helicobacter pylori infection.
Practitioner Question of the Month
Practice Tip
Case Study
Research
- Combination L-T3 and L-T4 Therapy for Hypothyroidism
- A Critical Appraisal of the Recent Reports on Sunbeds from the European Commission’s Scientific Committee on Health, Environmental and Emerging Risks and from the World Health Organization
- Elemental Diet and the Nutritional Treatment of Crohn’s Disease
- Rapid-Fire Research – Ultra-Concise Summaries of Noteworthy Studies
- Positive effects of resistant starch supplementation on bowel function in healthy adults: a systematic review and meta-analysis of randomized controlled trials.
- Lubiprostone accelerates intestinal transit and alleviates small intestinal bacterial overgrowth (SIBO) in patients with chronic constipation.
- Is thyroid autoimmunity itself associated with psychological well-being in euthyroid Hashimoto’s thyroiditis?
- Selenium supplementation could restore euthyroidism in subclinical hypothyroid patients with autoimmune thyroiditis.
- Effects of eight weeks of time-restricted feeding (16/8) on basal metabolism, maximal strength, body composition, inflammation, and cardiovascular risk factors in resistance-trained males.
Practitioner Question of the Month
Practice Tip
Case Study
Research
- Low FODMAP in 2017: Lessons Learned From Clinical Trials and Mechanistic Studies
- Effect of a Preparation of Four Probiotics on Symptoms of Patients with Irritable Bowel Syndrome: Association with Intestinal Bacterial Overgrowth
- 25-Hydroxyvitamin-D3 Serum Modulation After Use of Sunbeds Compliant with European Union Standards: A Randomized Open Observational Controlled Trial
- Rapid-Fire Research – Ultra-Concise Summaries of Noteworthy Studies
- Follow-Up of Patients with Functional Bowel Symptoms Treated with a Low FODMAP Diet
- Aberrant Motility in Unaffected Small Bowel is Linked to Inflammatory Burden and Patient Symptoms in Crohn’s Disease
- A Proof-of-Concept Study Showing Antibiotics to be More Effective in Irritable Bowel Syndrome With than Without Small Intestinal Bacterial Overgrowth: A Randomized, Double-Blind, Placebo-Controlled Trial
- Prevalence of Thyroid Dysfunction and Autoimmunity in the Older Population and Implications of Age-Specific Reference Ranges
- Subclinical Thyroid Dysfunction and the Risk of Cognitive Decline: A Meta-Analysis of Prospective Cohort Studies
- Factors Affecting Gastrointestinal Absorption of Levothyroxine: A Review
Practitioner Question of the Month
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Case Study
Research
- Methodology and Indications of H2-Breath Testing in Gastrointestinal Diseases: the Rome Consensus Conference
- A Systematic Review and Meta-Analysis of Interval Training Versus Moderate-Intensity Continuous Training on Body Adiposity.
- Measurement of Hydrogen Sulfide During Breath Testing Correlates to Patient Symptoms
Practitioner Question of the Month
Practice Tip
Case Study
Research
- Leptin in Autoimmune Diseases
- Clinical Trial: the Combination of Rifaximin With Partially Hydrolysed Guar Gum Is More Effective Than Rifaximin Alone in Eradicating Small Intestinal Bacterial Overgrowth
- Autoimmunity Affects Health-Related Quality of Life in Patients With Hashimoto’s Thyroiditis
- Bacillus as Potential Probiotics: Status, Concerns, and Future Perspectives
Practitioner Question of the Month
Practice Tip
Case Study
Research
- DIAGNOSIS OF ENDOCRINE DISEASE: How Reliable Are Free Thyroid and Total T3 Hormone Assays?
- The Omega-3 Index: A New Risk Factor for Death From Coronary Heart Disease.
- An Italian Prospective Multicenter Survey on Patients Suspected of Having Non-Celiac Gluten Sensitivity.
- Screening for Thyroid Cancer: US Preventive Services Task Force Recommendation Statement.
Practitioner Question of the Month
Practice Tip
Case Study
Research
- Abnormal breath testing in IBS: a meta-analysis
- Therapy options in irritable bowel syndrome
- Effect of rifaximin treatment on anti-vinculin antibodies in IBS with diarrhea
- A meta-analysis of Hashimoto’s thyroiditis and papillary thyroid carcinoma risk
Practitioner Question of the Month
Practice Tip
Case Study
Research
- The risks and benefits of sun exposure 2016, Review
- What is the clinical role of oral liquid preparations in the treatment of patients with hypothyroidism?
- The effect of the apolipoprotein E genotype on response to personalized dietary advice intervention: Findings from the Food4Me randomized controlled trial
- The low FODMAP diet: Recent advances in understanding its mechanisms and efficacy in IBS
Practitioner Question of the Month
Practice Tip
Case Study
Research
- Adrenal fatigue does not exist: A systematic review
- Intestinal dysbiosis and probiotic applications in autoimmune diseases.
- Diet’s (low FODMAP) effect on intestinal endocrine cells in IBS.
- Coffee and autoimmunity: More than a mere hot beverage!
Practitioner Question of the Month
Practice Tip
Case Study
Research
- Thyroid Antibody Interpretation, Selenium Supplementation, and the Gut-Thyroid Connection
- Folic Acid Reduces Stroke in Those with High Cholesterol and MTHFR
- Folic Acid Reduces Stroke in Those with High Homocysteine and MTHFR
- Helminth Therapy to Stabilize Mast Cells
Practitioner Question of the Month
Practice Tip
Case Study
Research
- Vaccination and thyroid autoimmunity
- A blood test for IBS & SIBO. Vinculin and CdtB antibodies, are they helpful?
- Is TSH alone adequate to assess thyroid function?
- Is using hydrogen peroxide as a mouthwash carcinogenic?
Practitioner Question of the Month
Practice Tip
Case Study
Research
- Probiotics causing brain fog in SIBO patients.
- Non-celiac gluten sensitivity and rheumatic diseases.
- Iodine and thyroid function.
- Resistant starch supplementation and bowel function
Practitioner Question of the Month
Practice Tip
Case study
Research
- Histamine intolerance and dietary management, a review.
- Hypothyroid and levothyroxine use, the strongest contributors to SIBO.
- Thyroid autoimmunity and psychological well-being.
- Hydrogen sulfide SIBO, validation for IBS and testing methods.
- Selenium for subclinical hypothyroidism.
Practitioner Question of the Month
Practice Tip
Case Study
Research
- A review of functional foods for cardiovascular health.
- SIBO breath testing – updates according to the North American consensus.
- Does microbiota composition affect thyroid homeostasis?
- Can sun or UV exposure reduce mortality?
- Do antibacterial personal care products impact the microbiota or metabolism?
Practitioner Question of the Month
Practice Tip
Case Study
Research
- Carbohydrate malabsorption and histamine intolerance
- Mast cells, histamine, and IBS
- H. pylori and autoimmunity
- Medical cannabis (marijuana) and autoimmune disease
Practitioner Question of the Month
Practice Tip
Case Study
Research
- Use of probiotics to correct dysbiosis of normal microbiota following disease or disruptive events: a systematic review.
- The Unintended Consequences of a Gluten-Free Diet.
- Repeat Treatment With Rifaximin is Safe and Effective in Patients With Diarrhea-Predominant Irritable Bowel Syndrome.
- Vitamin D improves thyroid autoimmunity in women already on levothyroxine
- Plant-animal subsistence ratios and macronutrient energy estimations in worldwide hunter-gatherer diets.
Practitioner Question of the Month
Practice Tip
Case Study
Research
- Vitamin B12 arrests stomach autoimmunity
- Treating SIBO: an evidence-based approach
- H. pylori and thyroid autoimmunity
- Sun exposure and invasive cancers
Practitioner Question of the Month
Practice Tip
Case Study
Research
- Low carbohydrate diets improve thyroid autoimmunity.
- Insufficient documentation for clinical efficacy of selenium supplementation in chronic autoimmune thyroiditis.
- Berberine successful for IBS, but there is a twist.
- Probiotics in IBS, a review of the literature.
Practitioner Question of the Month
Practice Tip
Case Study
Research
- Low FODMAP versus prebiotics in IBS, a head-to-head-trial.
- Anti-Thyroperoxidase Antibody Levels >500 IU/ml Indicate a Moderately Increased Risk for Developing Hypothyroidism in Autoimmune Thyroiditis.
- Gut-to-brain or brain-to-gut, which pathway is more important?
- Using SIBO breath testing to predict response to antibiotics in patients with IBS.
- An evidence based thyroid questionnaire.