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Do you want to start feeling better?

Yes, Where Do I Start?

Are Meal Replacement Shakes Good For You?

How, Why, and When to Choose Meal Replacement Shakes

Key Takeaways:
  • Meal replacement shakes have traditionally been about weight loss but can also be useful when your digestive system needs a bit of a break.
  • They also work as a healthy breakfast or to refuel and replenish muscles after hard exercise.
  • Meal replacement shakes have been shown to support healthy blood sugar and insulin sensitivity.
  • Look for meal replacement shakes that are low in added sugars, contain healthy fats and proteins, and are made with whole food ingredients.
  • Make sure to choose a meal replacement shake free from ingredients that you’re intolerant of (such as dairy or gluten).
    For really stubborn gut problems, an elemental diet is likely the better choice.

Eating a balanced, healthy diet can sometimes be a challenge, especially when you have the constraints of a hectic work schedule, travel, or gut sensitivities that make specific foods out of bounds.

This is where meal replacement shakes can be a help. A well-formulated complete meal replacement will provide balanced nutrition to fill the gap when you can’t or don’t want to cook, and can be a gentler alternative to chewing or processing solid foods when gut symptoms flare. Good quality meal replacements are also low in allergens and other possible food triggers, providing a useful rest for those with sensitive digestive systems.

The latest science supports the use of meal replacement shakes, especially in areas such as weight management and metabolic health. In this article, we’ll take a look at the when, what, and how of meal replacements so you know the best way to benefit from their use.

Meal replacement shake: woman drinking a protein shake while working

What Defines a ‘Meal Replacement Shake‘?

“Meal replacement” is the term used to describe a product (usually powdered, but sometimes a ready-to-drink shake) that replaces someone’s normal meal [1]. Typically, you’ll add water, cow’s milk, or a plant-based milk if you are dairy-free. 

You can also vary things up by adding fruit, Greek yogurt, or nut butter (for example, organic peanut butter), to your own taste. 

Meal replacement shakes are regulated differently in different countries, but in the U.S. are typically considered conventional foods. This means meal replacement products must:

  • Comply with all regulatory requirements for food
  • List every ingredient and a full Nutrition Facts panel

This isn’t, however, a guarantee of high-quality nutrition. You may have to do your research and read the labels on meal replacement shakes carefully. 

For example, you might want to check that the product gives you a good balance of carbs, proteins, and fats for your individual needs and doesn’t contain any allergens or ingredients you might be sensitive to. Some meal replacements may provide quality whole foods ingredients, while others can have more synthetic ingredients.

Who Might Use a Meal Replacement Shake?

Are Meal Replacement Shakes Good For You? - Why%20Try%20a%20Meal%20Replacement%20Shake Landscape L

There are several reasons you might want to use meal replacement shakes. These include general wellness and more specific health reasons:

Healthy nutrition on the go. Getting a healthy meal that isn’t loaded with additives, sugars and refined carbs can be difficult when traveling. A meal replacement shake is a much healthier option than grabbing fast food or food from a gas station.

Easier on the digestive system. For people who have gut issues or sensitivity to particular foods, a liquid (low allergen) shake is often easier to digest and assimilate than solid food.

Blood sugar control. Those who struggle with blood sugar or have pre-diabetes or other metabolic risk factors (such as high blood pressure or high cholesterol) may find meal replacements useful. 

An easy breakfast. A meal replacement powder made into a drink is a good choice if you can’t face food early in the morning. 

A post-workout snack. A high-protein meal replacement shake can be a convenient way to refuel and repair muscles after exercise. This is especially the case if it’s a while until your next scheduled full meal. 

Portion control. A low-calorie meal replacement shake that replaces a couple of your daily meals can help you lose weight or be an effective part of a healthy weight management diet. 

Benefits of Meal Replacements

Dumbbells, tumbler, scoop of protein powder, measuring tape and a bottle of water

A balanced diet of whole foods is the ideal, but when this isn’t possible, a high-quality meal replacement with transparent manufacturing processes and high-quality ingredients may actually improve your health.

Some of the benefits of meal replacements that have been documented include the following.

Blood Sugar & Metabolic Health Benefits

  • A 2018 randomized controlled trial (RCT) with 162 overweight/obese adults found that 16 weeks of using high-protein meal replacements as part of a calorie-controlled diet improved [2]:
    • Cholesterol
    • Triglycerides
    • Insulin
    • C-reactive protein (an inflammatory marker)
    • Blood glucose
    • Blood pressure
  • Another 2018 RCT of Type-2 diabetes patients found that full, or partial replacement of meals with shakes for 12 weeks improved hemoglobin A1c (a measure of average blood sugar over the past 2-3 months), fasting blood sugar, blood pressure, and weight [3].
  • A diabetes-specific nutritional shake for breakfast and as an afternoon snack also improved blood sugar control and reduced cravings for starchy foods [4].

Weight Loss 

  • When dieters using meal replacement shakes were compared with dieters on other diets (and both groups received standard levels of support), the meal replacement groups lost 5 lbs more on average, per year [5].
    • If meal replacement users received a higher level of psychological and practical support, the difference in weight loss was even higher — they lost 13.5 lbs more than standard dieters given standard support [5].
  • Twelve weeks of meal replacement shakes also curbed food cravings by 20% [6].

Improved Nutrient Intake

  • In one study, those who used replacement meal shakes ate fewer calories, less fat, and more protein, fiber, calcium, magnesium, iron, zinc, copper, vitamin E, vitamin C, thiamin, niacin, vitamin B6, and folate [7].
  • In another review, researchers looked for adverse effects of meal replacements, including whether they caused nutritional deficiencies. Two studies reported no health/medical issues with the shakes, while five more found that they actually improved the nutritional quality of the participants’ diets [5].

What to Look For in a Meal Shake

Fruits and vegetables in a bowls

As with your normal diet, good quality ingredients, and a healthy nutritional balance are what you should be looking for when you choose a meal replacement.

For people who still struggle from time to time with inflammation and gut sensitivities, I’d recommend these general pointers to help you choose a meal replacement shake:

Reduced or Low Carb

Though some people can cope with higher carb diets very well, many others can’t. If you have a gut imbalance, fermentable carbohydrates often create gas, bloating, and diarrhea symptoms, so it’s better to steer clear of them in large amounts [8].

In fact, finding your ideal intake of carbohydrates and prebiotics is one of the four pillars of healthy eating for gut healing that I focus on in Healthy Gut, Healthy You.

Meal replacement shake: Four Principles of a Healthy Diet infographic

Low Allergen

Depending on your individual sensitivities, you’ll need to choose a meal replacement shake that won’t upset your gut. To be on the safer side you may want to choose one that is free from common allergens — i.e. lactose-free, and dairy-free, soy-free, and gluten-free.

Good Quality Protein

Higher protein diets may help manage your weight and control blood pressure and levels of triglycerides in the blood [9]. Depending on your preferences and/or sensitivities, you may want to look into different protein sources.

For example, pea protein is a neutral-tasting vegan protein that works well in a meal shake. It also avoids the use of whey protein, which isn’t suitable for those with dairy intolerance.

Research has found pea protein to help with appetite suppression, improved muscle health, and lower cholesterol and blood pressure [10, 11].

Free From Artificial Sweeteners

I generally advise people with gut problems to avoid artificial sweeteners. The research isn’t conclusive in this area, but several animal studies show links between saccharin, aspartame, and sucralose and alterations in gut bacteria. Artificial sweeteners have also been linked with an uptick in intestinal and liver inflammation [12, 13, 14, 15].

Whole Food Focused 

In some meal shakes, the ingredients are highly processed or synthetically produced. However, the best meal replacement shakes provide naturally sourced antioxidants and essential vitamins, from whole superfood ingredients like berries and greens. 

Healthy Fats

Good fat is an essential part of any diet, including if you use meal shakes. Good fats include omega-3 — linked with better heart health [16] — and medium-chain triglycerides (MCTs). MCTs appear to improve cognitive function in some groups [17, 18] and have been linked with small improvements in body weight and composition (muscle/fat ratio) [19, 20]. They are also thought to potentially reduce insulin resistance [21, 22].

Elemental Diets Versus Meal Replacement Shakes

As well as standard meal replacement shakes, you may have also come across elemental diets, which are another form of meal shake. So which is best for you?

What’s an Elemental Diet?

An elemental diet supplies all of your essential vitamins and macronutrients (proteins, carbs, and fats), but in a pre-digested form that is very easy for your digestive system to deal with. So, for example, instead of protein, an elemental shake will contain its constituent amino acids. 

Elemental diets were first developed for patients with severe digestive issues [23, 24]. But over time, other useful applications of the elemental diet — even if used on an ad hoc basis — have been discovered.

For example, You may benefit from an elemental diet if:

  • You suffer from a stubborn gut imbalance. Research shows that the elemental diet can be helpful for IBD (Crohn’s disease and colitis) [25, 26], SIBO [27], IBS [27], and celiac disease [28]. Using an elemental diet for a week or two may start to turn things around when other gut therapies have failed.
  • You’re having an inflammatory flare. An elemental diet can also be very helpful to quickly relieve inflammation if your gut condition flares. Even a “half” elemental diet (up to 50% of daily calories from elemental shakes) for a time may reduce gut symptoms and flares [29].

How Elemental and Meal Replacement Shakes Compare

Like elemental diets, meal replacement shakes also provide proteins, carbohydrates, fats, and essential vitamins and minerals (such as vitamin C potassium and iron). But the nutrients are not pre-digested in the same way. 

While a meal replacement shake can be easier to digest than a solid meal, it may not be as effective when it comes to healing an extremely sensitive or inflamed gut.

In short:

  • If you’re having an acute symptomatic flare or need a complete gut reset: Choose an elemental formula if you are having an acute clinical flare in symptoms or need a complete gut reset.
  • A meal replacement shake is a good choice if you have some ongoing gut issues but have already made some headway in the gut healing process.
  • A meal replacement shake can be a good transition product between moving from a completely elemental diet to a completely solid one.

Meal Replacement Shakes: A Recap

When you need healthy, convenient nutrition on the run or that won’t upset a sensitive gut, a quality meal replacement shake is a good option. Replacing breakfast and/or lunch is the most usual practice, with a balanced meal making up your third meal of the day.

Meal replacement shakes aren’t a panacea for digestive issues and should be part of a wider gut-healing plan, for example, the one described in Healthy Gut, Healthy You

Some people with stubborn gut issues or other symptoms will benefit from more thorough investigations. If you are interested in a personal consultation, contact us at the Ruscio Institute

The Ruscio Institute has developed a range of high-quality formulations to help our patients and audience. If you’re interested in learning more about these products, please click here. Note that there are many other options available, and we encourage you to research which products may be right for you.

➕ References

  1. Regulatory Requirements for Meal Replacement Products: An International Review | RAPS [Internet]. Available from:
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  3. Kempf K, Röhling M, Niedermeier K, Gärtner B, Martin S. Individualized Meal Replacement Therapy Improves Clinically Relevant Long-Term Glycemic Control in Poorly Controlled Type 2 Diabetes Patients. Nutrients. 2018 Aug 4;10(8). DOI: 10.3390/nu10081022. PMID: 30081574. PMCID: PMC6115894.
  4. Mustad VA, Hegazi RA, Hustead DS, Budiman ES, Rueda R, Maki K, et al. Use of a diabetes-specific nutritional shake to replace a daily breakfast and afternoon snack improves glycemic responses assessed by continuous glucose monitoring in people with type 2 diabetes: a randomized clinical pilot study. BMJ Open Diabetes Res Care. 2020 Jul;8(1). DOI: 10.1136/bmjdrc-2020-001258. PMID: 32718934. PMCID: PMC7389484.
  5. Astbury NM, Piernas C, Hartmann-Boyce J, Lapworth S, Aveyard P, Jebb SA. A systematic review and meta-analysis of the effectiveness of meal replacements for weight loss. Obes Rev. 2019 Apr;20(4):569–87. DOI: 10.1111/obr.12816. PMID: 30675990. PMCID: PMC6849863.
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  7. Miller GD, Beavers DP, Hamm D, Mihalko SL, Messier SP. Nutrient Intake During Diet-Induced Weight Loss and Exercise Interventions in a Randomized Trial in Older Overweight and Obese Adults. J Nutr Health Aging. 2017;21(10):1216–24. DOI: 10.1007/s12603-017-0892-5. PMID: 29188882.
  8. The Low FODMAP Diet Approach: Effects of FODMAPs on the Gut – About IBS [Internet]. Available from:
  9. Santesso N, Akl EA, Bianchi M, Mente A, Mustafa R, Heels-Ansdell D, et al. Effects of higher- versus lower-protein diets on health outcomes: a systematic review and meta-analysis. Eur J Clin Nutr. 2012 Jul;66(7):780–8. DOI: 10.1038/ejcn.2012.37. PMID: 22510792. PMCID: PMC3392894.
  10. Lonnie M, Laurie I, Myers M, Horgan G, Russell WR, Johnstone AM. Exploring Health-Promoting Attributes of Plant Proteins as a Functional Ingredient for the Food Sector: A Systematic Review of Human Interventional Studies. Nutrients. 2020 Jul 30;12(8). DOI: 10.3390/nu12082291. PMID: 32751677. PMCID: PMC7468935.
  11. Smith CE, Mollard RC, Luhovyy BL, Anderson GH. The effect of yellow pea protein and fibre on short-term food intake, subjective appetite and glycaemic response in healthy young men. Br J Nutr. 2012 Aug;108 Suppl 1:S74-80. DOI: 10.1017/S0007114512000700. PMID: 22916818.
  12. Suez J, Korem T, Zeevi D, Zilberman-Schapira G, Thaiss CA, Maza O, et al. Artificial sweeteners induce glucose intolerance by altering the gut microbiota. Nature. 2014 Oct 9;514(7521):181–6. DOI: 10.1038/nature13793. PMID: 25231862.
  13. Bian X, Chi L, Gao B, Tu P, Ru H, Lu K. Gut microbiome response to sucralose and its potential role in inducing liver inflammation in mice. Front Physiol. 2017 Jul 24;8:487. DOI: 10.3389/fphys.2017.00487. PMID: 28790923. PMCID: PMC5522834.
  14. Olivier-Van Stichelen S, Rother KI, Hanover JA. Maternal Exposure to Non-nutritive Sweeteners Impacts Progeny’s Metabolism and Microbiome. Front Microbiol. 2019 Jun 20;10:1360. DOI: 10.3389/fmicb.2019.01360. PMID: 31281295. PMCID: PMC6595049.
  15. Rodriguez-Palacios A, Harding A, Menghini P, Himmelman C, Retuerto M, Nickerson KP, et al. The Artificial Sweetener Splenda Promotes Gut Proteobacteria, Dysbiosis, and Myeloperoxidase Reactivity in Crohn’s Disease-Like Ileitis. Inflamm Bowel Dis. 2018 Apr 23;24(5):1005–20. DOI: 10.1093/ibd/izy060. PMID: 29554272. PMCID: PMC5950546.
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  17. Avgerinos KI, Egan JM, Mattson MP, Kapogiannis D. Medium Chain Triglycerides induce mild ketosis and may improve cognition in Alzheimer’s disease. A systematic review and meta-analysis of human studies. Ageing Res Rev. 2020 Mar;58:101001. DOI: 10.1016/j.arr.2019.101001. PMID: 31870908. PMCID: PMC7050425.
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  19. Mumme K, Stonehouse W. Effects of medium-chain triglycerides on weight loss and body composition: a meta-analysis of randomized controlled trials. J Acad Nutr Diet. 2015 Feb;115(2):249–63. DOI: 10.1016/j.jand.2014.10.022. PMID: 25636220.
  20. Bueno NB, de Melo IV, Florêncio TT, Sawaya AL. Dietary medium-chain triacylglycerols versus long-chain triacylglycerols for body composition in adults: systematic review and meta-analysis of randomized controlled trials. J Am Coll Nutr. 2015 Feb 4;34(2):175–83. DOI: 10.1080/07315724.2013.879844. PMID: 25651239.
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  23. Borrelli O, Cordischi L, Cirulli M, Paganelli M, Labalestra V, Uccini S, et al. Polymeric diet alone versus corticosteroids in the treatment of active pediatric Crohn’s disease: a randomized controlled open-label trial. Clin Gastroenterol Hepatol. 2006 Jun;4(6):744–53. DOI: 10.1016/j.cgh.2006.03.010. PMID: 16682258.
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  25. Rajendran N, Kumar D. Role of diet in the management of inflammatory bowel disease. World J Gastroenterol. 2010 Mar 28;16(12):1442–8. DOI: 10.3748/wjg.v16.i12.1442. PMID: 20333783. PMCID: PMC2846248.
  26. Tsertsvadze A, Gurung T, Court R, Clarke A, Sutcliffe P. Clinical effectiveness and cost-effectiveness of elemental nutrition for the maintenance of remission in Crohn’s disease: a systematic review and meta-analysis. Health Technol Assess. 2015 Mar;19(26):1–138. DOI: 10.3310/hta19260. PMID: 25831484. PMCID: PMC4781042.
  27. Pimentel M, Constantino T, Kong Y, Bajwa M, Rezaei A, Park S. A 14-day elemental diet is highly effective in normalizing the lactulose breath test. Dig Dis Sci. 2004 Jan;49(1):73–7. DOI: 10.1023/b:ddas.0000011605.43979.e1. PMID: 14992438.
  28. Olaussen RW, Løvik A, Tollefsen S, Andresen PA, Vatn MH, De Lange T, et al. Effect of elemental diet on mucosal immunopathology and clinical symptoms in type 1 refractory celiac disease. Clin Gastroenterol Hepatol. 2005 Sep;3(9):875–85. DOI: 10.1016/s1542-3565(05)00295-8. PMID: 16234025.
  29. Takagi S, Utsunomiya K, Kuriyama S, Yokoyama H, Takahashi S, Iwabuchi M, et al. Effectiveness of an “half elemental diet” as maintenance therapy for Crohn’s disease: A randomized-controlled trial. Aliment Pharmacol Ther. 2006 Nov 1;24(9):1333–40. DOI: 10.1111/j.1365-2036.2006.03120.x. PMID: 17059514.

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