The Link Between MCAS, POTS, and EDS with Dr. Leonard Weinstock
Exploring the Link Between These Three Syndromes—Referred to as the “Evil Triad”
Mast cell activation (MCAS), Ehlers-Danlos syndrome (EDS), and postural orthostatic tachycardia syndrome (POTS) are three often debilitating conditions on their own, but it seems they’re likely connected to one another.
Join me and Dr. Weinstock as he explains the symptoms of these conditions, how they’re linked, and what the future looks like for treatment. Even if you’re only dealing with MCAS or POTS, this episode is worth a listen.
Featured Studies
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10352424/
- https://pubmed.ncbi.nlm.nih.gov/26976734/
- https://pubmed.ncbi.nlm.nih.gov/34618688/
- https://pubmed.ncbi.nlm.nih.gov/32824107/
- https://pubmed.ncbi.nlm.nih.gov/30022117/
- https://pubmed.ncbi.nlm.nih.gov/36337620/
- https://pubmed.ncbi.nlm.nih.gov/25640519/
- https://pubmed.ncbi.nlm.nih.gov/34496250/
- https://pubmed.ncbi.nlm.nih.gov/35636614/
- https://pubmed.ncbi.nlm.nih.gov/31421665/
- https://pubmed.ncbi.nlm.nih.gov/34441978/
- https://pubmed.ncbi.nlm.nih.gov/27741023/
- https://pubmed.ncbi.nlm.nih.gov/33629149/
- https://pubmed.ncbi.nlm.nih.gov/30118241/#:~:text=Conclusions%3A%20This%20study%20clearly%20confirms,controlled%20trial%20is%20thus%20warranted.
- https://pubmed.ncbi.nlm.nih.gov/35663980/
- https://pubmed.ncbi.nlm.nih.gov/27436071/
- https://pubmed.ncbi.nlm.nih.gov/23666445/
- https://pubmed.ncbi.nlm.nih.gov/29183244/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8537261/
Related Resources
- What is POTS: https://drruscio.com/pots/
- Choosing an MCAS diet: https://drruscio.com/mcas-diet/
- To contribute to the MCAS documentary: https://ldnresearchtrust.org/documentary-fundraiser
- More about LDN: https://ldnresearchtrust.org/what-is-low-dose-naltrexone-ldn
- Courses, free guides, and more: https://drruscio.com/resources?utm_source=youtube&utm_medium=link&utm_campaign=drruscio.com_resources
Timestamps
00:00 Intro
01:06 What is the “triad”?
02:58 MCAS, POTS, & EDS defined
14:33 What are effective therapeutics for healing?
17:20 Approach to MCAS: Step 1
18:14 The importance of mental health
27:32 How these immune symptoms connect to gut health
33:18 Where Dr. Weinstock starts with stomach distension
36:32 Immunoglobulins
38:50 Sodium butyrate
39:42 The low FODMAP diet for dysbiosis
42:30 Effective therapies for POTS & EDS
47:39 Low-dose naltrexone
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DISCLAIMER: The information on this site is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified healthcare provider before starting any new treatment or discontinuing an existing treatment.
Music featured in this video: “Modern Technology” by Andrew G, https://audiojungle.net/user/andrew_g
*Full transcript available on YouTube by clicking the “Show transcript” button on the bottom right of the video.
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Dr. Michael Ruscio is a DC, Naturopathic Practitioner, researcher, and clinician. He serves as an Adjunct Professor at the University of Bridgeport and has published numerous papers in scientific journals as well as the book Healthy Gut, Healthy You. He also founded the Ruscio Institute of Functional Health, where he helps patients with a wide range of GI conditions and serves as the Head of Research.
➕ Dr. Ruscio’s Notes
MCAS
➕ Resources & Links
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Discussion
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