Dr. Ruscio’s Wrap Up #151

Dr. Ruscio’s Wrap Up #151

Dr. Ruscio’s Wrap Up #151

In Case You Missed It

On Monday, we discussed a listener question, “Which Should I Do?” regarding functional medicine tests.

On Wednesday’s podcast release, we spoke with the Mind Pump Crew and discussed all things gut health.


Latest Research

This study seeks to understand the long-term response to gluten free diet as evidence for non-celiac wheat sensitive patients that have diarrhea-dominant and mixed-type irritable bowel syndrome. About one third of the patients in the study with IBS-D or IBS-M are wheat sensitive. The study concludes that expression of HLA-DQ2/8 is not useful as diagnostic marker for wheat sensitivity.

Can Lactobacillus gasseri strain CP2305 have a positive effect on quality of life, clinical symptoms and change gene expression in patients with IBS? Patients received CP2305 daily for 4 weeks and compared to the placebo group, the IBS-severity index score was significantly improved. They also saw a reduction in health-related worry and changes in intestinal microbiota. The change in gene expression was linked to improvement in IBS severity. This study demonstrated that CP2305 administration beneficially influences IBS patients in both subjective and objective evaluations, and gene expression profiling provided insights into the functional mechanism.”

36 studies (64,628 subjects) published between 1955 and 2016 from 13 countries were identified to determine if there is an association between Hashimoto’s Thyroiditis and Thyroid Cancer. They found a relative risk of Hashimoto’s thyroiditis (HT) among papillary thyroid cancer (PTC) of 2.36, a relative risk of PTC among HT of 1.40, and a relative risk of thyroid lymphoma (TL) among HT of 9.74. From those findings, they reported an association between HT and PTC and between HT and TL. “No association was found between HT and follicular, medullary, or anaplastic thyroid cancer.”

Recent trials have shown that fecal microbiota transplantation (FMT) is a promising treatment to induce remission in ulcerative colitis. Key components are repeated enemas and using high-diversity FMT donors. “Out of 20 patients enrolled in the study, 7 patients (35%) achieved a clinical response by week four, 4 patients (20%) were in remission at week four, 3 patients (15%) required escalation of care.” A microbiome analysis also revealed that restricted diversity of recipients pre-FMT was significantly increased. “Notably donor composition correlated with clinical response.”

There may be a high risk of bias in randomized controlled studies of the Low FODMAP diet. The diet has not been studied in a randomized, controlled setting for more than 6 weeks and trials examining the effect of the important reintroduction period are lacking. There is a risk that the symptomatic effects reported in the trials are driven primarily by a placebo response.”


Laugh a Little!


Healthy Foodie

Joyful Healthy Eats: Baked Garlic Parmesan Potato Wedges
PaleoLeap: Turkey and Mushroom Salad
Skinny Taste: Pollo in Potacchio
Our Paleo Life: Keto Pumpkin Layer Cheesecake


Happiness Homework 

Sip a cup of tea, look out the window, and let your mind wander.


Dr. Ruscio’s Quotable

“No act of kindness, no matter how small, is ever wasted.”
— Aesop

What do you think? I would like to hear your thoughts on the research, recipes and other info above.

I care about answering your questions and sharing my knowledge with you. Comment below with any health question you may have and I will incorporate it into our new monthly podcast just for you!

Dr. Ruscio is your leading functional and integrative doctor specializing in gut related disorders such as SIBO, leaky gut, Celiac, IBS and in thyroid disorders such as hypothyroid and hyperthyroid. For more information on how to become a patient, please contact our office. Serving the San Francisco bay area and distance patients via phone and Skype.

Discussion

I care about answering your questions and sharing my knowledge with you. Leave a comment or connect with me on social media asking any health question you may have and I just might incorporate it into our next listener questions podcast episode just for you!

6 thoughts on “Dr. Ruscio’s Wrap Up #151

  1. Ironic that we can put a person on the moon, save people with heart disease with triple by pass surgery, and we can’t heal depression. I’m aware of the mind gut connection, but it is complicated. I started having flares of IBSd at the age of 13. I also experienced my first episode of depression that over the years became worse and each episode longer. I’ve been high functioning but have struggled and found I’ve lost a lot to these illnesses. I’ve done everything to help myself with diet, meditation, exercise, yoga, and drugs. There have been times I despaired to the point of contemplating suicide. In my 20’s I.decided not to have children because I was told my children would have a 50/50 chance of inheriting the “depressive” gene. I couldn’t do this to a child. Now my 12 year old niece has been diagnosed with depression. And she has IBS. This really kills me. How much do genetics play in all this?

    1. Depression and IBS can occur together. I often see mood improved when improving someones gut, and published literature is starting to support this. Genetics yes, but you can change those. I would optimize her gut health and see what happens to her mood, could be very helpful. My book lays out the tools you need to get started.

  2. Dr. Ruscio,
    I wish I could give you a big hug!!
    Thank you so much for writing this book. I first saw you in a webcast with Dr. Perlmutter and immediately ordered your book on Kindle and now on Amazon.
    I’ve been sick with, God knows what, gut issues for a few years now and it has been getting progressively worse. I recently got a diagnosis of Microscopic Colitis, (a problem that does NOT get the respect it deserves!). Anyway, the Gastro gave me Pepto, with instructions to come back for Endocort if I didn’t get relief. The Pepto helped in as much as I could eventually leave my house again, but there is so much more healing to do. I believe there is more going on than the MC and want to get to the root of why it’s there in the first place not just throw meds at it.

    I have become the person you talk about who see themselves in every symptom list, Each time elated to have at last found what is making me sick! I rush out and buy a fortune of supplements, diet foods etc., only to get back where I started, sometimes with a little improvement, but always with a lot of frustration.
    I have learned so much, but could not organize all the information. There is so much overlap in symptoms and so much contradictory diet and supplemental advise!! I ended up with information paralysis, not knowing what to do next but feeling really scared because I know I have to do something or continue downhill.
    That is when I heard you talk! OMG! I have hope again! You have taken all that information swirling in my head made it understandable and put it in a logical roadmap for me!
    I feel so much better with a step by step plan to work through!
    Again, thank you so much!
    I hope to write to you again and tell you how healthy I am feeling!
    God Bless you!

  3. Dr. Ruscio,
    I wish I could give you a big hug!!
    Thank you so much for writing this book. I first saw you in a webcast with Dr. Perlmutter and immediately ordered your book on Kindle and now on Amazon.
    I’ve been sick with, God knows what, gut issues for a few years now and it has been getting progressively worse. I recently got a diagnosis of Microscopic Colitis, (a problem that does NOT get the respect it deserves!). Anyway, the Gastro gave me Pepto, with instructions to come back for Endocort if I didn’t get relief. The Pepto helped in as much as I could eventually leave my house again, but there is so much more healing to do. I believe there is more going on than the MC and want to get to the root of why it’s there in the first place not just throw meds at it.

    I have become the person you talk about who see themselves in every symptom list, Each time elated to have at last found what is making me sick! I rush out and buy a fortune of supplements, diet foods etc., only to get back where I started, sometimes with a little improvement, but always with a lot of frustration.
    I have learned so much, but could not organize all the information. There is so much overlap in symptoms and so much contradictory diet and supplemental advise!! I ended up with information paralysis, not knowing what to do next but feeling really scared because I know I have to do something or continue downhill.
    That is when I heard you talk! OMG! I have hope again! You have taken all that information swirling in my head made it understandable and put it in a logical roadmap for me!
    I feel so much better with a step by step plan to work through!
    Again, thank you so much!
    I hope to write to you again and tell you how healthy I am feeling!
    God Bless you!

  4. Ironic that we can put a person on the moon, save people with heart disease with triple by pass surgery, and we can’t heal depression. I’m aware of the mind gut connection, but it is complicated. I started having flares of IBSd at the age of 13. I also experienced my first episode of depression that over the years became worse and each episode longer. I’ve been high functioning but have struggled and found I’ve lost a lot to these illnesses. I’ve done everything to help myself with diet, meditation, exercise, yoga, and drugs. There have been times I despaired to the point of contemplating suicide. In my 20’s I.decided not to have children because I was told my children would have a 50/50 chance of inheriting the “depressive” gene. I couldn’t do this to a child. Now my 12 year old niece has been diagnosed with depression. And she has IBS. This really kills me. How much do genetics play in all this?

    1. Depression and IBS can occur together. I often see mood improved when improving someones gut, and published literature is starting to support this. Genetics yes, but you can change those. I would optimize her gut health and see what happens to her mood, could be very helpful. My book lays out the tools you need to get started.

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