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Noora Alakulppi

PhD

Dr. Noora Alakulppi is a human geneticist and Precision Nutrition Level 2 nutrition coach with expertise in nutrition, autoimmune, gastrointestinal, and hormonal diseases. In 2008, Dr. Alakulppi graduated with her Doctor of Philosophy degree from the University of Helsinki Department of Biosciences. In post-graduate time, she researched celiac disease diagnostics, stem cells, and gastrointestinal microbiome. She is currently completing her Functional Medicine Nutrition Coach education in Finland. Her research interests include quantitative self/biohacking, supplements, herbs, spices, and the big four: stress, sleep, movement, and social connections. In her spare time, Dr. Alakulppi enjoys piano playing and singing.

Education

  • University of Helsinki, PhD Genetics
  • EVTEK University of Applied Sciences, BS Biotechnology Engineering

Certifications

  • Advanced Certificate in Coaching Dietary Strategies
  • Advanced Certificate in Nutrition Coaching for Athletes
  • Advanced Certificate in Nutrition for Metabolic Health
  • Nutrition Instructor
  • Advanced Certification in Change Psychology
  • Precision Nutrition Level 1, Certificate in Sleep, Stress Management, and Recovery Coaching
  • Certified Project Management Associate IPMA Level D
  • Precision Nutrition Level 2 Certified Master Coach
  • Precision Nutrition Level 1 Certified Nutrition Coach

Affiliations

Publications

  • Impola, U., Turpeinen, H., Alakulppi, N., Linjama, T., Volin, L., Niittyvuopio, . . . Koskela, S. (2014). Donor Haplotype B of NK KIR receptor reduces the relapse risk in HLA-identical sibling hematopoietic stem cell transplantation of AML patients. Frontiers in Immunology, 5(405), 1–5. doi:10.3389/fimmu.2014.00405
  • Partanen, J., Kosdela, S., Alakulppi, N., Linjama, T., Impola, U., Peräsaari, J., & Volin, L. (2014). Donor KIR B-haplotype reduces the risk of relapse in HLA identical allogeneic hematopoietic stem cell transplantation in Finland. Tissue Antigens, 84.
  • Wacklin, P., Tuimala, J., Nikkilä, J., Tims, S., Mäkivuokko, H., Alakulppi, N., . . . Mättö, J. (2014). Faecal microbiota composition in adults Is associated with the FUT2 gene determining the secretor status. PLOS ONE, 9(4), e94863, doi:10.1371/journal.pone.0094863
  • Joda, H., Beni, V., Alakulppi, N., Partanen, J., Lind, K., Strömbom, L., . . . O’Sullivan, C. K. (2014). Medium-high resolution electrochemical genotyping of HLA-DQ2/DQ8 for detection of predisposition to coeliac disease. Analytical and Bioanalytical Chemistry, 406(12). doi:10.1007/s00216-014-7650-x
  • Parmar, A. S., Alakulppi, N., Paavola-Sakki, P., Kurppa, K., Halme, L., Färkkilä . . . Einarsdottir, E. (2012). Association study of FUT2 (rs601338) with celiac disease and inflammatory bowel disease in the Finnish population. Tissue Antigens, 80(6). doi:http://dx.doi.org/10.1111/tan.12016
  • Mäkivuokko, H., Wacklin, P., Koenen, M. E., Laamanen, K., Alakulppi, N., Venema K., & Mättö, J. (2012). Isolation of bifidobacteria for blood group secretor status targeted personalised nutrition. Microbial Ecology in Health and Disease, 23. doi: 10.3402/mehd.v23i0.18578
  • Joda, H., Beni, V., Curnane, D., Katakis, I., Alakulppi, N., Partanen, J., . . . O’Sullivan, C. K. (2012). Low-medium resolution HLA-DQ2/DQ8 typing for coeliac disease predisposition analysis by colorimetric assay. Analytical and Bioanalytical Chemistry, 403(3), 807–819. doi:10.1007/s00216-012-5898-6
  • Haimila, K., Alakulppi, N., & Partanen, J. (2011). Immune gene polymorphisms associate with outcome in kidney transplantation. In M. Trzcinska (Ed.), Kidney Transplantation–New Perspectives.
  • Ortiz, M., del Valle, M. T., Alakulppi, N., Strömbom, L., Fragoso, A., & O’Sullivan, C. K. (2011). Amperometric supramolecular genosensor self-assembled on cyclodextrin-modified surfaces. Electrochemistry Communications, 13(6), 578–581. doi:10.1016/j.elecom.2011.03.014
  • Wacklin, P., Mäkivuokko, H., Alakulppi, N., Nikkilä, Tenkanen, H., Räbinä, J., . . . Mättö. (2011). Secretor genotype (FUT2 gene) is strongly associated with the composition of Bifidobacteria in the human intestine. PLOS ONE, 6(5), e20113. doi:10.1371/journal.pone.0020113
  • Haimila, K., Turpeinen, H., Alakulppi, N., Kyllönen, L. E., Salmela, K. T., & Partanen, J. (2009). Association of genetic variation in inducible costimulator gene with outcome of kidney transplantation. Transplantation, 87(3), 393–396. doi:10.1097/TP.0b013e318192897a
  • Alakulppi, N., Seikku, P., Jaatinen, T., Holmberg, C., & Laine, J. (2008). Feasibility of diagnosing subclinical renal allograft rejection in children by whole blood gene expression analysis. Transplantation, 86(9), 1222–1228. doi:10.1097/TP.0b013e3181883fb0
  • Alakulppi, N., Kyllönen, L. E., Partanen, J., Salmela, K. T., & Laine, J. (2008). Lack of association between thrombosis-associated and cytokine candidate gene polymorphisms and acute rejection or vascular complications after kidney transplantation. Nephrology Dialysis Transplantation, 23(1), 364–368. doi:http://dx.doi.org/10.1093/ndt/gfm528
  • Alakulppi, N. (2008). Genetic aspects of outcome in kidney transplantation: cytokine and thrombosis associated candidate genes and gene expression biomarkers. (Doctoral dissertation, University of Helsinki, Finland).
  • Alakulppi, N., Kyllönen, L. E., Partanen, J., Salmela, K. T., & Laine, J. (2007). Diagnosis of acute renal allograft rejection by analyzing whole blood mRNA expression of lymphocyte marker molecules. Transplantation, 83(6), 791–798. doi:10.1097/01.tp.0000258726.13363.ab
  • Alakulppi, N., Kyllönen, L. E., Salo, H. M. E., Partanen, J., Salmela, K. T., & Laine, J. (2006). The impact of donor cytokine gene polymorphisms on the incidence of cytomegalovirus infection after kidney transplantation. Transplant Immunology, 16(3–4), 258–262. doi:10.1016/j.trim.2006.09.007
  • Roivainen, M., Alakulppi, N., Ylipaasto, P., Eskelinen, M., Paananen, A., Airaksinen, A., & Hovi, T. (2006). A whole cell immunization-derived monoclonal antibody that protects cells from coxsackievirus A9 infection binds to both cell surface and virions. Journal of Virological Methods, 130(1–2), 108–116. doi:10.1016/j.jviromet.2005.06.012
  • Laine, J., Jalanko, H., Alakulppi, N., & Holmberg, C. (2005). A new tubular disorder with hypokalaemic metabolic alkalosis, severe hypermagnesuric hypomagnesaemia, hypercalciuria and cardiomyopathy. Nephrology Dialysis Transplantation, 20I(6), 1241–1245. doi:10.1093/ndt/gfh760
  • Alakulppi, N., Kyllönen, L. E., Jäntti, V. T., Matinlauri, I., Partanen, J., Salmela, K. T., & Laine, J. (2004). Cytokine gene polymorphisms and risks of acute rejection and delayed graft function after kidney transplantation. Transplantation, 78(10), 1422–1428. doi:10.1097/01.TP.0000140884.71571.BC
  • Säilä, H., Pitkäniemi, J., Tuomilehto, J., Savolainen, A., Alakulppi, N., Tuomilehto-Wolf, E., . . . Aho, K. (2004). HLA and susceptibility to juvenile idiopathic arthritis: A study of affected sibpairs in an isolated Finnish population. 
  • Alakulppi, N., Kyllönen, L. E., Jäntti, V. T., Partanen, J. A., Salmela, K. T., & Laine, J. (2004). Cytokine polymorphisms and risks of acute rejection and delayed graft function after kidney transplantation. American Journal of Transplantation, 4.
  • Säilä, H., Savolainen, A., Kauppi, M. J., Alakulppi, N., Tuomilehto-Wolf, E., Tuomilehto, J., . . . Aho, K. (2003). Occurrence of chronic inflammatory rheumatic diseases among parents of multiple offspring affected by juvenile idiopathic arthritis. Clinical and Experimental Rheumatology, 21(2), 263–265.
  • Alakulppi, N., Saila, H., Savolainen, A., Tuomilehto-Wolf, E., & Tuomilehto, E. (2002). HLA haplotype (A,C,B,DRB1,DQB1) sharing in Finnish families with multiple siblings affected by juvenile idiopathic arthritis. Tissue Antigens, 59, 55.

Areas of special interest: nutrition, autoimmunity, gastrointestinal disease, hormonal disease

Noora Alakulppi

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